MolNFT v1 · #104106 · protein
Crystal structure of acinetobacter sp. DL28 L-ribose isomerase in complex with L-ribulose
4Q0Q: “Crystal structure of acinetobacter sp. DL28 L-ribose isomerase in complex with L-ribulose”. X-ray diffraction, 4 ligands (RUU, QDK, NCO), 3 pockets (best druggability 0.70). MolNFT v1 #104106 on GenesisL1: 3D structure, binding…
- PDB
- 4Q0Q
- Type
- protein
- Length
- 249 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L-ribose isomerase
- EC
- 5.3.1.-
- UniProt
- Q93UQ5
- Ligands
- RUU, QDK, NCO, CO
- Pockets
- 3 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 22% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L-ribose isomerase (EC 5.3.1.-) | protein | 249 | 22% helix, 27% strand | Q93UQ5 |
Ligands and binding sites
- RUU · alpha-L-ribulofuranose · ligand · 7 copies · chains A
- QDK · L-ribulose · ligand · chains A
- NCO · Cobalt hexammine(iii) · ligand · chains A
- CO · Cobalt (II) ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 294 | 0.70 | 0.84 | 46 | RUU, QDK |
| 2 | 65 | 0.31 | 0.75 | 13 | empty |
| 3 | 85 | 0.31 | 0.73 | 16 | empty |
Compared structures
- 4Q0Q · Crystal structure of Acinetobacter sp. DL28 L-ribose isomerase in complex with L-ribulose · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93UQ5
- Elsewhere: RCSB PDB 4Q0Q · PDBe 4Q0Q · UniProt Q93UQ5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.