MolNFT v1 · #102911 · protein
The T6 backbone pilin of serotype M6 streptococcus pyogenes has a modular three-domain structure decorated with variable loops and extensions
4P0D · Trypsin-resistant surface T6 protein: “The T6 backbone pilin of serotype M6 streptococcus pyogenes has a modular three-domain structure decorated…”. X-ray diffraction, 2 ligands (CA, IOD), 3 pockets (best druggability 0.52). MolNFT…
- PDB
- 4P0D
- Type
- protein
- Length
- 471 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Trypsin-resistant surface T6 protein
- UniProt
- P18481
- Ligands
- CA, IOD
- Pockets
- 3 · best druggability 0.52
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Trypsin-resistant surface T6 protein | protein | 471 | 6% helix, 47% strand | P18481 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 154 | 0.52 | 0.80 | 33 | empty |
| 2 | 129 | 0.47 | 0.79 | 33 | empty |
| 3 | 55 | 0.28 | 0.74 | 20 | empty |
Modifications
Observed in the structure: 2 isopeptide (isopeptide).
Compared structures
- 4P0D · The T6 backbone pilin of serotype M6 Streptococcus pyogenes has a modular three-domain… · the same entry in another collection · chain A against A, TM-score 1.00
- P18481 · AlphaFold monomer V2.0 prediction for trypsin-resistant surface T6 protein (P18481) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P18481
- Elsewhere: RCSB PDB 4P0D · PDBe 4P0D · UniProt P18481
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