MolNFT v1 · #102788 · protein
Crystal structure of the nemo cozi in complex with hoip NZF1 domain
4OWF · Nf-kappa-B essential modulator: “Crystal structure of the nemo cozi in complex with hoip NZF1 domain”. X-ray diffraction, 1 ligand (ZN). MolNFT v1 #102788 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4OWF
- Type
- protein
- Length
- 198 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nf-kappa-B essential modulator; E3 ubiquitin-protein ligase RNF31
- EC
- 6.3.2.-
- UniProt
- O88522, Q96EP0
- Ligands
- ZN
Structure
x-ray diffraction · 3 distinct chains · 82% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nf-kappa-B essential modulator (EC 6.3.2.-) | protein | 83 | 96% helix, 0% strand | O88522 |
| B | Nf-kappa-B essential modulator (EC 6.3.2.-) | protein | 86 | 97% helix, 0% strand | O88522 |
| G | E3 ubiquitin-protein ligase RNF31 (EC 6.3.2.-) | protein | 29 | 0% helix, 21% strand | Q96EP0 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains G
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
3 interfaces between chains.
- A–B · 2421 Ų buried · 9 hydrogen bonds · protein-protein
- B–G · 359 Ų buried · 5 hydrogen bonds · protein-protein
- A–G · 231 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 4OWF · Crystal structure of the NEMO CoZi in complex with HOIP NZF1 domain · the same entry in another collection · chain A against A, TM-score 1.00
- Q96EP0 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RNF31 (Q96EP0) · a predicted model of the same protein · chain G against A, TM-score 0.91
- O88522 · AlphaFold monomer V2.0 prediction for nf-kappa-B essential modulator (O88522) · a predicted model of the same protein · chain A against A, TM-score 0.81
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O88522
- Every structure of UniProt Q96EP0
- Elsewhere: RCSB PDB 4OWF · PDBe 4OWF · UniProt O88522 · UniProt Q96EP0
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