UniProt O88522
Nf-kappa-B essential modulator (O88522)
Nf-kappa-B essential modulator (UniProt O88522): 12 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O88522
- Protein
- Nf-kappa-B essential modulator
- Experimental structures
- 12
- Predicted models
- 1
Structures
13 records of O88522 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2V4H | NEMO CC2-LZ domain - 1D5 DARPin complex | x-ray diffraction | A, B | — | — |
| 2V4H | Nemo CC2-lz domain - 1D5 darpin complex | x-ray diffraction | A, B | — | — |
| 2ZVN | NEMO CoZi domain incomplex with diubiquitin in P212121 space group | x-ray diffraction | B, D, F, H | — | — |
| 2ZVN | Nemo cozi domain incomplex with diubiquitin in P212121 space group | x-ray diffraction | B, D, F, H | — | — |
| 2ZVO | NEMO CoZi domain in complex with diubiquitin in C2 space group | x-ray diffraction | B, D | — | — |
| 2ZVO | Nemo cozi domain in complex with diubiquitin in C2 space group | x-ray diffraction | B, D | — | — |
| 3F89 | NEMO CoZi domain | x-ray diffraction | A, B | — | — |
| 3F89 | Nemo cozi domain | x-ray diffraction | A, B | — | — |
| 3JSV | Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin | x-ray diffraction | C, D | — | — |
| 3JSV | Crystal structure of mouse nemo cozi in complex with LYS63-linked di- ubiquitin | x-ray diffraction | C, D | — | — |
| 4OWF | Crystal structure of the NEMO CoZi in complex with HOIP NZF1 domain | x-ray diffraction | A, B | — | — |
| 4OWF | Crystal structure of the nemo cozi in complex with hoip NZF1 domain | x-ray diffraction | A, B | — | — |
| O88522 | AlphaFold monomer V2.0 prediction for nf-kappa-B essential modulator (O88522) | predicted | A | — | — |
Experiment against prediction
- 3JSV chain C against the predicted model O88522: TM-score 0.91, RMSD 1.13 Å
- 3JSV chain C against the predicted model O88522: TM-score 0.91, RMSD 1.13 Å
- 2ZVN chain B against the predicted model O88522: TM-score 0.89, RMSD 1.23 Å
- 2ZVN chain B against the predicted model O88522: TM-score 0.89, RMSD 1.23 Å
- 2ZVN chain F against the predicted model O88522: TM-score 0.88, RMSD 1.28 Å
- 2ZVN chain F against the predicted model O88522: TM-score 0.88, RMSD 1.28 Å
- 2ZVN chain D against the predicted model O88522: TM-score 0.85, RMSD 1.45 Å
- 2ZVN chain D against the predicted model O88522: TM-score 0.85, RMSD 1.45 Å
- 2ZVO chain B against the predicted model O88522: TM-score 0.82, RMSD 1.69 Å
- 2ZVO chain B against the predicted model O88522: TM-score 0.82, RMSD 1.69 Å
Elsewhere
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