MolNFT v1 · #10184 · protein
CA2+-bound structure of multidomain ef-hand protein, CBP40, from true slime mold
1IJ6 · Plasmodial specific LAV1-2 protein: “CA2+-bound structure of multidomain ef-hand protein, CBP40, from true slime mold”. X-ray diffraction, 1 ligand (CA), 3 pockets (best druggability 0.51). MolNFT v1 #10184 on GenesisL1: 3D…
- PDB
- 1IJ6
- Type
- protein
- Length
- 305 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Plasmodial specific LAV1-2 protein
- UniProt
- P14725
- Ligands
- CA
- Pockets
- 3 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 67% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Plasmodial specific LAV1-2 protein | protein | 305 | 67% helix, 3% strand | P14725 |
Ligands and binding sites
- CA · Calcium ion · metal · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 206 | 0.51 | 0.77 | 25 | empty |
| 2 | 53 | 0.30 | 0.76 | 13 | empty |
| 3 | 53 | 0.25 | 0.73 | 17 | empty |
Compared structures
- 1IJ6 · CA2+-bound structure of multidomain ef-hand protein, CBP40, from true slime mold · the same entry in another collection · chain A against A, TM-score 1.00
- P14725 · AlphaFold monomer V2.0 prediction for plasmodial-specific protein LAV1-2 (P14725) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14725
- Elsewhere: RCSB PDB 1IJ6 · PDBe 1IJ6 · UniProt P14725
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.