MolNFT v1 · #539931 · protein
AlphaFold monomer V2.0 prediction for zinc finger and btb domain- containing protein 7A (O95365)
O95365 · Zinc finger and btb domain-containing protein 7A: “AlphaFold monomer V2.0 prediction for zinc finger and btb domain- containing protein 7A (O95365)”. 7 pockets (best druggability 0.69). MolNFT v1 #539931 on GenesisL1: 3D…
- Accession
- O95365
- Type
- protein
- Length
- 584 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7012c0b45c68a2c067644b9d3e5DDa06892c6957
- Molecule
- Zinc finger and btb domain-containing protein 7A
- UniProt
- O95365
- Pockets
- 7 · best druggability 0.69
Structure
1 distinct chain · 34% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Zinc finger and btb domain-containing protein 7A | protein | 584 | 34% helix, 5% strand | O95365 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 876 | 0.69 | 0.75 | 61 | empty |
| 2 | 189 | 0.52 | 0.77 | 30 | empty |
| 3 | 132 | 0.49 | 0.79 | 35 | empty |
| 4 | 145 | 0.40 | 0.74 | 21 | empty |
| 5 | 85 | 0.39 | 0.78 | 18 | empty |
Compared structures
- 2IF5 · Structure of the poz domain of human lrf, a master regulator of oncogenesis · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 2IF5 · Structure of the POZ domain of human LRF, a master regulator of oncogenesis · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 2NN2 · Crystal structure of the btb domain from the LRF/ZBTB7 transcriptional regulator · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 2NN2 · Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 8E3D · ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing CAST sequence (#11) · an experimental structure of the same protein · chain A against B, TM-score 0.17
- 7EYI · Crystal structure of ZBTB7A in complex with gamma-globin -200 sequence element with… · an experimental structure of the same protein · chain A against G, TM-score 0.17
- 7EYI · Crystal structure of ZBTB7A in complex with gamma-globin -200 sequence element with… · an experimental structure of the same protein · chain A against G, TM-score 0.17
- 7N5S · ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 6) · an experimental structure of the same protein · chain A against A, TM-score 0.17
- 7N5S · ZBTB7A zinc finger domain bound to -200 site of fetal globin promoter (oligo 6) · an experimental structure of the same protein · chain A against A, TM-score 0.17
- 7N5T · ZBTB7A zinc finger domain bound to -200 site of fetal globin promoter (oligo 5) · an experimental structure of the same protein · chain A against A, TM-score 0.17
- 7N5T · ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 5) · an experimental structure of the same protein · chain A against A, TM-score 0.17
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O95365
- Elsewhere: UniProt O95365 · AlphaFold DB O95365
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