MolNFT v1 · #507563 · protein
AlphaFold monomer V2.0 prediction for ADP-ribose glycohydrolase AF_1521 (O28751)
O28751: “AlphaFold monomer V2.0 prediction for ADP-ribose glycohydrolase AF_1521 (O28751)”. 1 pocket (best druggability 0.56). MolNFT v1 #507563 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O28751
- Type
- protein
- Length
- 192 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x275eb680a4a33D3dDEd594ef59526457E1E4749D
- Molecule
- ADP-ribose glycohydrolase AF_1521
- UniProt
- O28751
- Pockets
- 1 · best druggability 0.56
Structure
1 distinct chain · 44% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ADP-ribose glycohydrolase AF_1521 | protein | 192 | 44% helix, 22% strand | O28751 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 199 | 0.56 | 0.79 | 32 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 2BFQ · Macro domains are ADP-ribose binding molecules · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 2BFQ · Macro domains are ADP-ribose binding molecules · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 2BFR · The macro domain is an ADP-ribose binding module · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 2BFR · The Macro domain is an ADP-ribose binding module · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 6FX7 · Crystal structure of in vitro evolved Af1521 · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 6FX7 · Crystal structure of in vitro evolved AF1521 · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 1VHU · Crystal structure of a putative phosphoesterase · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 1VHU · Crystal structure of a putative phosphoesterase · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 1HJZ · Crystal structure of AF1521 protein containing a MACROH2A domain · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1HJZ · Crystal structure of AF1521 protein containing a macroH2A domain · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 7WR6 · Crystal structure of ADP-riboxanated caspase-4 in complex with Af1521 · an experimental structure of the same protein · chain A against B, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O28751
- Elsewhere: UniProt O28751 · AlphaFold DB O28751
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