UniProt O28751
ADP-ribose glycohydrolase AF_1521 (O28751)
ADP-ribose glycohydrolase AF_1521 (UniProt O28751): 9 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O28751
- Protein
- ADP-ribose glycohydrolase AF_1521
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
10 records of O28751 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HJZ | Crystal structure of AF1521 protein containing a macroH2A domain | x-ray diffraction | A, B | — | — |
| 1HJZ | Crystal structure of AF1521 protein containing a MACROH2A domain | x-ray diffraction | A, B | — | — |
| 1VHU | Crystal structure of a putative phosphoesterase | x-ray diffraction | A | — | — |
| 1VHU | Crystal structure of a putative phosphoesterase | x-ray diffraction | A | — | — |
| 2BFQ | Macro domains are ADP-ribose binding molecules | x-ray diffraction | A | — | — |
| 2BFQ | Macro domains are ADP-ribose binding molecules | x-ray diffraction | A | — | — |
| 2BFR | The Macro domain is an ADP-ribose binding module | x-ray diffraction | A | — | — |
| 2BFR | The macro domain is an ADP-ribose binding module | x-ray diffraction | A | — | — |
| 6FX7 | Crystal structure of in vitro evolved AF1521 | x-ray diffraction | A | AR6 | — |
| O28751 | AlphaFold monomer V2.0 prediction for ADP-ribose glycohydrolase AF_1521 (O28751) | predicted | A | — | 1 (best 0.56) |
Ligands
- AR6 · [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2R,3S,4R,5S)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate · in 1 record
Experiment against prediction
- 2BFQ chain A against the predicted model O28751: TM-score 1.00, RMSD 0.24 Å
- 2BFQ chain A against the predicted model O28751: TM-score 1.00, RMSD 0.24 Å
- 2BFR chain A against the predicted model O28751: TM-score 1.00, RMSD 0.25 Å
- 2BFR chain A against the predicted model O28751: TM-score 1.00, RMSD 0.25 Å
- 6FX7 chain A against the predicted model O28751: TM-score 0.99, RMSD 0.28 Å
- 1VHU chain A against the predicted model O28751: TM-score 1.00, RMSD 0.30 Å
- 1VHU chain A against the predicted model O28751: TM-score 1.00, RMSD 0.30 Å
- 1HJZ chain A against the predicted model O28751: TM-score 0.99, RMSD 0.46 Å
- 1HJZ chain A against the predicted model O28751: TM-score 0.99, RMSD 0.46 Å
Elsewhere
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