GL1X · GenesisL1 explorer

MolNFT v1 · #502378 · protein

AlphaFold monomer V2.0 prediction for xylosyltransferase 1 (Q86Y38)

Q86Y38: “AlphaFold monomer V2.0 prediction for xylosyltransferase 1 (Q86Y38)”. 9 pockets (best druggability 0.76). MolNFT v1 #502378 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q86Y38
Type
protein
Length
959 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x8F642c1bE4c8282d76b08B1077D11CCF2e2D16DB
Molecule
Xylosyltransferase 1
UniProt
Q86Y38
Pockets
9 · best druggability 0.76

Structure

1 distinct chain · 25% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AXylosyltransferase 1protein95925% helix, 19% strandQ86Y38

Pockets

9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18690.760.7978empty
25200.690.7951empty
31580.470.7722empty
4990.460.8016empty
5510.460.8513empty

Modifications

Observed in the structure: 7 disulfide (disulfide).

Compared structures

  • 6EJ7 · Human xylosyltransferase 1 in complex with udp-xylose and peptide qeeegagggqgg · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 6EJ7 · Human Xylosyltransferase 1 in complex with UDP-xylose and peptide QEEEGAGGGQGG · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 6EJ8 · Human Xylosyltransferase 1 in complex with peptide QEEEGSGGGQGG · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 6EJ8 · Human xylosyltransferase 1 in complex with peptide qeeegsgggqgg · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 6EJB · Human xylosyltransferase 1 in complex with peptide qeeegsaggqgg · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 6EJB · Human Xylosyltransferase 1 in complex with peptide QEEEGSAGGQGG · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 6EJ9 · Human xylosyltransferase 1 in complex with peptide qepegsgggqgg · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 6EJ9 · Human Xylosyltransferase 1 in complex with peptide QEPEGSGGGQGG · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 6EJC · Human xylosyltransferase 1 in complex with peptide qeeegsgvgqgg · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 6EJC · Human Xylosyltransferase 1 in complex with peptide QEEEGSGVGQGG · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 6FOA · Human xylosyltransferase 1 apo structure · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 6FOA · Human Xylosyltransferase 1 apo structure · an experimental structure of the same protein · chain A against A, TM-score 0.73

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