MolNFT v1 · #502237 · protein
AlphaFold monomer V2.0 prediction for xylose isomerase (P24300)
P24300: “AlphaFold monomer V2.0 prediction for xylose isomerase (P24300)”. 3 pockets (best druggability 0.66). MolNFT v1 #502237 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P24300
- Type
- protein
- Length
- 388 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x378a28002909c2509a47F088Dee431D1ba770530
- Molecule
- Xylose isomerase
- UniProt
- P24300
- Pockets
- 3 · best druggability 0.66
Structure
1 distinct chain · 49% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Xylose isomerase | protein | 388 | 49% helix, 10% strand | P24300 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 508 | 0.66 | 0.78 | 46 | empty |
| 2 | 71 | 0.47 | 0.83 | 14 | empty |
| 3 | 98 | 0.35 | 0.73 | 18 | empty |
Compared structures
- 2GLK · High-resolution study of D-Xylose isomerase, 0.94A resolution. · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 2GLK · High-resolution study of D-xylose isomerase, 0.94A resolution. · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 4QE1 · Room temperature X-ray structure of D-xylose isomerase in complex with two Cd2+ ions and… · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 4QE4 · Room temperature X-ray structure of D-xylose isomerase in complex with two Ni2+ ions and… · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 3QZA · Joint neutron and X-ray structure of apo-D-Xylose Isomerase at pH=5.9 · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 3QZA · Joint neutron and X-ray structure of apo-D-xylose isomerase at PH=5.9 · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 3KBV · Room temperature structure of D-Xylose Isomerase in complex with 2Ni(2+) co-factors · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 3KBV · Room temperature structure of D-xylose isomerase in complex with 2NI(2+) co-factors · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 4DVO · Room-temperature joint X-ray/neutron structure of D-xylose isomerase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 3KCJ · Room temperature neutron structure of apo-D-xylose isomerase (refined jointly with X-ray… · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 3KCJ · Room temperature neutron structure of apo-D-Xylose Isomerase (refined jointly with X-ray… · an experimental structure of the same protein · chain A against A, TM-score 1.00
- 4QDP · Joint X-ray and neutron structure of Streptomyces rubiginosus D-xylose isomerase in… · an experimental structure of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24300
- Elsewhere: UniProt P24300 · AlphaFold DB P24300
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