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AlphaFold monomer V2.0 prediction for xylose isomerase (P24300)

Analyse AlphaFold monomer V2.0 prediction for xylose isomerase (P24300) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P24300
Type
protein
Length
388 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x378a28002909c2509a47F088Dee431D1ba770530
Molecule
Xylose isomerase
UniProt
P24300
Pockets
3 · best druggability 0.66

Structure

1 distinct chain · 49% helix, 10% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AXylose isomeraseprotein38849% helix, 10% strandP24300

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15080.660.7846empty
2710.470.8314empty
3980.350.7318empty

Compared structures

  • 2GLK · High-resolution study of D-Xylose isomerase, 0.94A resolution. · an experimental structure of the same protein · chain A against A, TM-score 1.00
  • 2GLK · High-resolution study of D-xylose isomerase, 0.94A resolution. · an experimental structure of the same protein · chain A against A, TM-score 1.00
  • 4QE1 · Room temperature X-ray structure of D-xylose isomerase in complex with two Cd2+ ions and… · an experimental structure of the same protein · chain A against A, TM-score 1.00
  • 4QE4 · Room temperature X-ray structure of D-xylose isomerase in complex with two Ni2+ ions and… · an experimental structure of the same protein · chain A against A, TM-score 1.00
  • 3QZA · Joint neutron and X-ray structure of apo-D-Xylose Isomerase at pH=5.9 · an experimental structure of the same protein · chain A against A, TM-score 1.00
  • 3QZA · Joint neutron and X-ray structure of apo-D-xylose isomerase at PH=5.9 · an experimental structure of the same protein · chain A against A, TM-score 1.00
  • 3KBV · Room temperature structure of D-Xylose Isomerase in complex with 2Ni(2+) co-factors · an experimental structure of the same protein · chain A against A, TM-score 1.00
  • 3KBV · Room temperature structure of D-xylose isomerase in complex with 2NI(2+) co-factors · an experimental structure of the same protein · chain A against A, TM-score 1.00
  • 4DVO · Room-temperature joint X-ray/neutron structure of D-xylose isomerase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 1.00
  • 3KCJ · Room temperature neutron structure of apo-D-xylose isomerase (refined jointly with X-ray… · an experimental structure of the same protein · chain A against A, TM-score 1.00
  • 3KCJ · Room temperature neutron structure of apo-D-Xylose Isomerase (refined jointly with X-ray… · an experimental structure of the same protein · chain A against A, TM-score 1.00
  • 4QDP · Joint X-ray and neutron structure of Streptomyces rubiginosus D-xylose isomerase in… · an experimental structure of the same protein · chain A against A, TM-score 1.00

Analyse

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