MolNFT v1 · #499039 · protein
AlphaFold monomer V2.0 prediction for ribosome biogenesis protein WDR12 (Q9GZL7)
Q9GZL7: “AlphaFold monomer V2.0 prediction for ribosome biogenesis protein WDR12 (Q9GZL7)”. 4 pockets (best druggability 0.75). MolNFT v1 #499039 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9GZL7
- Type
- protein
- Length
- 423 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x8B93fC6fBA6a2FFED9121055984A688045C2f656
- Molecule
- Ribosome biogenesis protein WDR12
- UniProt
- Q9GZL7
- Pockets
- 4 · best druggability 0.75
Structure
1 distinct chain · 9% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribosome biogenesis protein WDR12 | protein | 423 | 9% helix, 48% strand | Q9GZL7 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 720 | 0.75 | 0.80 | 64 | empty |
| 2 | 152 | 0.40 | 0.73 | 23 | empty |
| 3 | 90 | 0.35 | 0.74 | 16 | empty |
| 4 | 51 | 0.32 | 0.77 | 11 | empty |
Compared structures
- 8FKY · Human nucleolar pre-60S ribosomal subunit (State F) · an experimental structure of the same protein · chain A against SP, TM-score 0.89
- 6N31 · Wd repeats of human WDR12 · an experimental structure of the same protein · chain A against B, TM-score 0.73
- 6N31 · WD repeats of human WDR12 · an experimental structure of the same protein · chain A against B, TM-score 0.73
- 6P0Q · Crystal Structure of Ubiquitin-like Domain of Human WDR12 · an experimental structure of the same protein · chain A against B, TM-score 0.22
- 6P0Q · Crystal structure of ubiquitin-like domain of human WDR12 · an experimental structure of the same protein · chain A against A, TM-score 0.21
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9GZL7
- Elsewhere: UniProt Q9GZL7 · AlphaFold DB Q9GZL7
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