UniProt Q9GZL7

Ribosome biogenesis protein WDR12 (Q9GZL7)

Ribosome biogenesis protein WDR12 (UniProt Q9GZL7): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q9GZL7
Protein: Ribosome biogenesis protein WDR12
Experimental structures: 5
Predicted models: 1
Ligands: 1
Pockets: 9 · 2 records with a druggable one

Structures

6 records of Q9GZL7 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6N31	WD repeats of human WDR12	x-ray diffraction	A, B	UNX	3 (best 0.76)
6N31	Wd repeats of human WDR12	x-ray diffraction	A, B	UNX	—
6P0Q	Crystal Structure of Ubiquitin-like Domain of Human WDR12	x-ray diffraction	A, B	—	2 (best 0.31)
6P0Q	Crystal structure of ubiquitin-like domain of human WDR12	x-ray diffraction	A, B	—	—
8FKY	Human nucleolar pre-60S ribosomal subunit (State F)	electron microscopy	SP	—	—
Q9GZL7	AlphaFold monomer V2.0 prediction for ribosome biogenesis protein WDR12 (Q9GZL7)	predicted	A	—	4 (best 0.75)

Ligands

UNX · Unknown atom or ion · in 2 records

Experiment against prediction

6N31 chain A against the predicted model Q9GZL7: TM-score 0.98, RMSD 1.09 Å
6N31 chain A against the predicted model Q9GZL7: TM-score 0.98, RMSD 1.09 Å
6N31 chain B against the predicted model Q9GZL7: TM-score 0.98, RMSD 1.15 Å
6N31 chain B against the predicted model Q9GZL7: TM-score 0.98, RMSD 1.15 Å
6P0Q chain B against the predicted model Q9GZL7: TM-score 0.95, RMSD 0.93 Å
8FKY chain SP against the predicted model Q9GZL7: TM-score 0.95, RMSD 1.87 Å
6P0Q chain A against the predicted model Q9GZL7: TM-score 0.94, RMSD 1.34 Å
6P0Q chain A against the predicted model Q9GZL7: TM-score 0.94, RMSD 1.34 Å

Elsewhere

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