MolNFT v1 · #499002 · protein
AlphaFold monomer V2.0 prediction for wd repeat and hmg-box DNA- binding protein 1 (O75717)
O75717 · Wd repeat and hmg-box DNA-binding protein 1: “AlphaFold monomer V2.0 prediction for wd repeat and hmg-box DNA- binding protein 1 (O75717)”. 10 pockets (best druggability 0.83). MolNFT v1 #499002 on GenesisL1: 3D structure, binding…
- Accession
- O75717
- Type
- protein
- Length
- 1,129 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
- Molecule
- Wd repeat and hmg-box DNA-binding protein 1
- UniProt
- O75717
- Pockets
- 10 · best druggability 0.83
Structure
1 distinct chain · 14% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Wd repeat and hmg-box DNA-binding protein 1 | protein | 1129 | 14% helix, 27% strand | O75717 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 619 | 0.83 | 0.87 | 40 | empty |
| 2 | 247 | 0.82 | 0.95 | 34 | empty |
| 3 | 730 | 0.76 | 0.81 | 59 | empty |
| 4 | 240 | 0.62 | 0.81 | 20 | empty |
| 5 | 96 | 0.47 | 0.80 | 18 | empty |
Compared structures
- 5OGS · Crystal structure of human and-1 sepb domain · an experimental structure of the same protein · chain A against A, TM-score 0.36
- 5OGS · Crystal structure of human AND-1 SepB domain · an experimental structure of the same protein · chain A against A, TM-score 0.36
- 6XTY · Cryoem structure of human cmg bound to and-1 (cmga) · an experimental structure of the same protein · chain A against F, TM-score 0.36
- 5GVB · Sepb domain of human and-1 · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 5GVA · WD40 domain of human and-1 · an experimental structure of the same protein · chain A against A, TM-score 0.27
- 2D7L · Solution structure of the hmg box domain from human wd repeat and hmg- box DNA binding… · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2D7L · Solution structure of the HMG box domain from human WD repeat and HMG-box DNA binding… · an experimental structure of the same protein · chain A against A, TM-score 0.05
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75717
- Elsewhere: UniProt O75717 · AlphaFold DB O75717
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