UniProt O75717
WD repeat and HMG-box DNA-binding protein 1 (O75717)
WD repeat and HMG-box DNA-binding protein 1 (UniProt O75717): 8 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75717
- Protein
- WD repeat and HMG-box DNA-binding protein 1
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 13 · 3 records with a druggable one
Structures
9 records of O75717 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2D7L | Solution structure of the HMG box domain from human WD repeat and HMG-box DNA binding protein 1 | solution nmr | A | — | — |
| 2D7L | Solution structure of the hmg box domain from human wd repeat and hmg- box DNA binding protein 1 | solution nmr | A | — | — |
| 5GVA | WD40 domain of human and-1 | x-ray diffraction | A | — | — |
| 5GVB | Sepb domain of human and-1 | x-ray diffraction | A | — | — |
| 5OGS | Crystal structure of human AND-1 SepB domain | x-ray diffraction | A | — | 2 (best 0.71) |
| 5OGS | Crystal structure of human and-1 sepb domain | x-ray diffraction | A | — | — |
| 6XTY | Cryoem structure of human cmg bound to and-1 (cmga) | electron microscopy | F, G, H | — | — |
| 7PLO | H. sapiens replisome-CUL2/LRR1 complex | electron microscopy | H, I, J | — | 1 (best 0.90) |
| O75717 | AlphaFold monomer V2.0 prediction for wd repeat and hmg-box DNA- binding protein 1 (O75717) | predicted | A | — | 10 (best 0.83) |
Experiment against prediction
- 5OGS chain A against the predicted model O75717: TM-score 1.00, RMSD 0.27 Å
- 5OGS chain A against the predicted model O75717: TM-score 1.00, RMSD 0.27 Å
- 6XTY chain F against the predicted model O75717: TM-score 1.00, RMSD 0.27 Å
- 5GVB chain A against the predicted model O75717: TM-score 1.00, RMSD 0.29 Å
- 5GVA chain A against the predicted model O75717: TM-score 0.99, RMSD 0.62 Å
- 7PLO chain J against the predicted model O75717: TM-score 0.97, RMSD 1.19 Å
- 7PLO chain H against the predicted model O75717: TM-score 0.97, RMSD 1.27 Å
- 7PLO chain I against the predicted model O75717: TM-score 0.88, RMSD 0.99 Å
- 2D7L chain A against the predicted model O75717: TM-score 0.67, RMSD 1.93 Å
- 2D7L chain A against the predicted model O75717: TM-score 0.67, RMSD 1.93 Å
Elsewhere
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