AlphaFold monomer V2.0 prediction for tryptophan synthase alpha chain (P00929)

Structure

1 distinct chain · 49% helix, 15% strand (DSSP).

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 4HPX · Crystal structure of Tryptophan Synthase at 1.65 A resolution in complex with alpha… · an experimental structure of the same protein · chain A against A, TM-score 0.99
• 4HPJ · Crystal structure of Tryptophan Synthase at 1.45 A resolution in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.99
• 4HN4 · Tryptophan synthase in complex with alpha aminoacrylate E(A-A) form and the F9 inhibitor… · an experimental structure of the same protein · chain A against A, TM-score 0.99
• 4HT3 · The crystal structure of Salmonella typhimurium Tryptophan Synthase at 1.30A complexed… · an experimental structure of the same protein · chain A against A, TM-score 0.99
• 4KKX · Crystal structure of Tryptophan Synthase from Salmonella typhimurium with 2-aminophenol… · an experimental structure of the same protein · chain A against A, TM-score 0.99
• 1K3U · Crystal structure of wild-type tryptophan synthase complexed with… · an experimental structure of the same protein · chain A against A, TM-score 0.99
• 1K3U · Crystal structure of wild-type tryptophan synthase complexed with N… · an experimental structure of the same protein · chain A against A, TM-score 0.99
• 6D0V · Tryptophan synthase Q114A mutant in complex with inhibitor… · an experimental structure of the same protein · chain A against A, TM-score 0.98
• 1TJP · Crystal structure of wild-type tryptophan synthase complexed with 1… · an experimental structure of the same protein · chain A against A, TM-score 0.98
• 1TJP · Crystal Structure Of Wild-Type Tryptophan Synthase Complexed With… · an experimental structure of the same protein · chain A against A, TM-score 0.98
• 4XUG · Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.98
• 1WBJ · wildtype tryptophan synthase complexed with glycerol phosphate · an experimental structure of the same protein · chain A against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P00929
• Elsewhere: UniProt P00929 · AlphaFold DB P00929