AlphaFold monomer V2.0 prediction for risc-loading complex subunit TARBP2 (Q15633)

Structure

1 distinct chain · 31% helix, 20% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 5N8L · Structure of trbp dsrbd 1 and 2 in complex with a 19 bp siRNA (complex B) · an experimental structure of the same protein · chain A against A, TM-score 0.41
• 5N8L · Structure of TRBP dsRBD 1 and 2 in complex with a 19 bp siRNA (Complex B) · an experimental structure of the same protein · chain A against A, TM-score 0.41
• 5N8M · Structure of trbp dsrbd 1 and 2 in complex with a 19 bp siRNA (complex a) · an experimental structure of the same protein · chain A against A, TM-score 0.40
• 5N8M · Structure of TRBP dsRBD 1 and 2 in complex with a 19 bp siRNA (Complex A) · an experimental structure of the same protein · chain A against A, TM-score 0.40
• 6ZBK · Crystal structure of the human complex between RPAP3 and trbp · an experimental structure of the same protein · chain A against B, TM-score 0.28
• 4WYQ · Crystal structure of the dicer-trbp interface · an experimental structure of the same protein · chain A against B, TM-score 0.20
• 4WYQ · Crystal structure of the Dicer-TRBP interface · an experimental structure of the same protein · chain A against B, TM-score 0.20
• 2CPN · Solution structure of the second dsrbd of tar RNA-binding protein 2 · an experimental structure of the same protein · chain A against A, TM-score 0.20
• 2CPN · Solution structure of the second dsRBD of TAR RNA-binding protein 2 · an experimental structure of the same protein · chain A against A, TM-score 0.20
• 5ZAK · Cryo-EM structure of human dicer and its complexes with a pre-miRNA substrate · an experimental structure of the same protein · chain A against B, TM-score 0.20
• 5ZAM · Cryo-EM structure of human dicer and its complexes with a pre-miRNA substrate · an experimental structure of the same protein · chain A against B, TM-score 0.20
• 3ADL · Structure of TRBP2 and its molecule implications for miRNA processing · an experimental structure of the same protein · chain A against A, TM-score 0.19

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q15633
• Elsewhere: UniProt Q15633 · AlphaFold DB Q15633