UniProt Q15633
RISC-loading complex subunit TARBP2 (Q15633)
RISC-loading complex subunit TARBP2 (UniProt Q15633): 16 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15633
- Protein
- RISC-loading complex subunit TARBP2
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 6 · 2 records with a druggable one
Structures
17 records of Q15633 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2CPN | Solution structure of the second dsRBD of TAR RNA-binding protein 2 | solution nmr | A | — | — |
| 2CPN | Solution structure of the second dsrbd of tar RNA-binding protein 2 | solution nmr | A | — | — |
| 3ADL | Structure of TRBP2 and its molecule implications for miRNA processing | x-ray diffraction | A | — | — |
| 3ADL | Structure of TRBP2 and its molecule implications for miRNA processing | x-ray diffraction | A | — | — |
| 3LLH | Crystal structure of the first dsRBD of TAR RNA-binding protein 2 | x-ray diffraction | A, B | — | — |
| 3LLH | Crystal structure of the first dsrbd of tar RNA-binding protein 2 | x-ray diffraction | A, B | — | — |
| 4WYQ | Crystal structure of the Dicer-TRBP interface | x-ray diffraction | B, E | — | — |
| 4WYQ | Crystal structure of the dicer-trbp interface | x-ray diffraction | B, E | — | — |
| 5N8L | Structure of TRBP dsRBD 1 and 2 in complex with a 19 bp siRNA (Complex B) | solution nmr | A | — | 2 (best 0.61) |
| 5N8L | Structure of trbp dsrbd 1 and 2 in complex with a 19 bp siRNA (complex B) | solution nmr | A | — | — |
| 5N8M | Structure of TRBP dsRBD 1 and 2 in complex with a 19 bp siRNA (Complex A) | solution nmr | A | — | 3 (best 0.63) |
| 5N8M | Structure of trbp dsrbd 1 and 2 in complex with a 19 bp siRNA (complex a) | solution nmr | A | — | — |
| 5ZAK | Cryo-EM structure of human dicer and its complexes with a pre-miRNA substrate | electron microscopy | B | — | — |
| 5ZAL | Cryo-EM structure of human dicer and its complexes with a pre-miRNA substrate | electron microscopy | B | — | — |
| 5ZAM | Cryo-EM structure of human dicer and its complexes with a pre-miRNA substrate | electron microscopy | B | — | — |
| 6ZBK | Crystal structure of the human complex between RPAP3 and trbp | x-ray diffraction | B | — | — |
| Q15633 | AlphaFold monomer V2.0 prediction for risc-loading complex subunit TARBP2 (Q15633) | predicted | A | — | 1 (best 0.33) |
Experiment against prediction
- 6ZBK chain B against the predicted model Q15633: TM-score 0.98, RMSD 0.65 Å
- 3LLH chain B against the predicted model Q15633: TM-score 0.96, RMSD 0.56 Å
- 3LLH chain B against the predicted model Q15633: TM-score 0.96, RMSD 0.56 Å
- 4WYQ chain B against the predicted model Q15633: TM-score 0.96, RMSD 0.63 Å
- 4WYQ chain B against the predicted model Q15633: TM-score 0.96, RMSD 0.63 Å
- 5N8L chain A against the predicted model Q15633: TM-score 0.96, RMSD 1.04 Å
- 5N8L chain A against the predicted model Q15633: TM-score 0.96, RMSD 1.04 Å
- 5N8M chain A against the predicted model Q15633: TM-score 0.91, RMSD 1.78 Å
- 5N8M chain A against the predicted model Q15633: TM-score 0.91, RMSD 1.78 Å
- 3LLH chain A against the predicted model Q15633: TM-score 0.90, RMSD 1.04 Å
Elsewhere
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