GL1X · GenesisL1 explorer

MolNFT v1 · #472061 · protein

AlphaFold monomer V2.0 prediction for trafficking protein particle complex II-specific subunit 130 (Q03660)

Q03660: “AlphaFold monomer V2.0 prediction for trafficking protein particle complex II-specific subunit 130 (Q03660)”. 13 pockets (best druggability 0.78). MolNFT v1 #472061 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q03660
Type
protein
Length
1,102 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x1ca26b2054BD7B7ddbC95b4914Ca7303754fF64e
Molecule
Trafficking protein particle complex II-specific subunit 130
UniProt
Q03660
Pockets
13 · best druggability 0.78

Structure

1 distinct chain · 36% helix, 31% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATrafficking protein particle complex II-specific subunit 130protein110236% helix, 31% strandQ03660

Pockets

13 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
19840.780.8069empty
28090.730.7863empty
31970.480.7520empty
4570.480.8415empty
51040.470.7919empty

Compared structures

  • 7U06 · Structure of the yeast TRAPPII-Rab11/Ypt32 complex in the closed/open state (composite… · an experimental structure of the same protein · chain A against B, TM-score 0.53
  • 7U05 · Structure of the yeast TRAPPII-Rab11/Ypt32 complex in the closed/closed state (composite… · an experimental structure of the same protein · chain A against B, TM-score 0.48
  • 7E93 · Intact TRAPPII (state III). · an experimental structure of the same protein · chain A against T, TM-score 0.47
  • 7E2C · Monomer of trappii (open) · an experimental structure of the same protein · chain A against I, TM-score 0.47
  • 7E2C · Monomer of TRAPPII (open) · an experimental structure of the same protein · chain A against I, TM-score 0.47
  • 7E94 · Intact TRAPPII (State II) · an experimental structure of the same protein · chain A against T, TM-score 0.47
  • 7E94 · Intact trappii (state II) · an experimental structure of the same protein · chain A against T, TM-score 0.47
  • 7E93 · Intact trappii (state III). · an experimental structure of the same protein · chain A against I, TM-score 0.47
  • 7EA3 · Intact Ypt32-TRAPPII (dimer). · an experimental structure of the same protein · chain A against I, TM-score 0.44

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