MolNFT v1 · #471556 · protein
AlphaFold monomer V2.0 prediction for thrombopoietin receptor (Q08351)
Q08351: “AlphaFold monomer V2.0 prediction for thrombopoietin receptor (Q08351)”. 9 pockets (best druggability 0.64). MolNFT v1 #471556 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q08351
- Type
- protein
- Length
- 625 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1141c59a573b52725A219545C456190739feD131
- Molecule
- Thrombopoietin receptor
- UniProt
- Q08351
- Pockets
- 9 · best druggability 0.64
Structure
1 distinct chain · 13% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thrombopoietin receptor | protein | 625 | 13% helix, 32% strand | Q08351 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 470 | 0.64 | 0.77 | 42 | empty |
| 2 | 155 | 0.61 | 0.84 | 28 | empty |
| 3 | 410 | 0.61 | 0.76 | 36 | empty |
| 4 | 112 | 0.47 | 0.79 | 19 | empty |
| 5 | 104 | 0.39 | 0.76 | 22 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q08351
- Elsewhere: UniProt Q08351 · AlphaFold DB Q08351
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