UniProt Q08351
Thrombopoietin receptor,GCN4 isoform 1 (Q08351)
Thrombopoietin receptor,GCN4 isoform 1 (UniProt Q08351): 1 experimental structure and 1 predicted model on GenesisL1, 2 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q08351
- Protein
- Thrombopoietin receptor,GCN4 isoform 1
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 25 · 2 records with a druggable one
Structures
2 records of Q08351 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8U18 | Cryo-EM structure of murine Thrombopoietin receptor ectodomain in complex with Tpo | electron microscopy | A, B | NAG, MAN | 16 (best 0.81) |
| Q08351 | AlphaFold monomer V2.0 prediction for thrombopoietin receptor (Q08351) | predicted | A | — | 9 (best 0.64) |
Ligands
Experiment against prediction
- 8U18 chain A against the predicted model Q08351: TM-score 0.89, RMSD 2.70 Å
- 8U18 chain B against the predicted model Q08351: TM-score 0.86, RMSD 2.48 Å
Elsewhere
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