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MolNFT v1 · #469294 · protein

AlphaFold monomer V2.0 prediction for trinucleotide repeat-containing gene 6C protein (Q9HCJ0)

Q9HCJ0: “AlphaFold monomer V2.0 prediction for trinucleotide repeat-containing gene 6C protein (Q9HCJ0)”. 2 pockets (best druggability 0.37). MolNFT v1 #469294 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9HCJ0
Type
protein
Length
1,690 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x4d07E6a23DeB6B95bd9b90EcB67368b7e8D3B77e
Molecule
Trinucleotide repeat-containing gene 6C protein
UniProt
Q9HCJ0
Pockets
2 · best druggability 0.37

Structure

1 distinct chain · 9% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATrinucleotide repeat-containing gene 6C proteinprotein16909% helix, 2% strandQ9HCJ0

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1670.370.7813empty
2630.300.7512empty

Compared structures

  • 2X04 · Crystal structure of the PABC-TNRC6C complex · an experimental structure of the same protein · chain A against C, TM-score 0.01
  • 2X04 · Crystal structure of the pabc-TNRC6C complex · an experimental structure of the same protein · chain A against C, TM-score 0.01
  • 3KTP · Structural basis of GW182 recognition by poly(A)-binding protein · an experimental structure of the same protein · chain A against B, TM-score 0.01
  • 3KTP · Structural basis of GW182 recognition by POLY(A)-binding protein · an experimental structure of the same protein · chain A against B, TM-score 0.01
  • 7RUQ · Structure of the human GIGYF1-TNRC6C complex · an experimental structure of the same protein · chain A against D, TM-score 0.00
  • 7RUQ · Structure of the human GIGYF1-TNRC6C complex · an experimental structure of the same protein · chain A against D, TM-score 0.00

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