MolNFT v1 · #442684 · protein
AlphaFold monomer V2.0 prediction for SWI/SNF global transcription activator complex subunit SWP82 (P43554)
P43554: “AlphaFold monomer V2.0 prediction for SWI/SNF global transcription activator complex subunit SWP82 (P43554)”. 10 pockets (best druggability 0.67). MolNFT v1 #442684 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P43554
- Type
- protein
- Length
- 623 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9188600a0FCa2914254C94299b1bd9721Bc4D500
- Molecule
- SWI/SNF global transcription activator complex subunit SWP82
- UniProt
- P43554
- Pockets
- 10 · best druggability 0.67
Structure
1 distinct chain · 35% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SWI/SNF global transcription activator complex subunit SWP82 | protein | 623 | 35% helix, 8% strand | P43554 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 738 | 0.67 | 0.75 | 58 | empty |
| 2 | 207 | 0.61 | 0.82 | 25 | empty |
| 3 | 184 | 0.57 | 0.80 | 19 | empty |
| 4 | 351 | 0.53 | 0.73 | 45 | empty |
| 5 | 131 | 0.49 | 0.79 | 32 | empty |
Compared structures
- 7C4J · Cryo-EM structure of the yeast SWI/SNF complex in a nucleosome free state · an experimental structure of the same protein · chain A against E, TM-score 0.21
- 7C4J · Cryo-EM structure of the yeast Swi/Snf complex in a nucleosome free state · an experimental structure of the same protein · chain A against E, TM-score 0.21
- 7EGM · The srm module of SWI/SNF-nucleosome complex · an experimental structure of the same protein · chain A against J, TM-score 0.18
- 7EGM · The SRM module of SWI/SNF-nucleosome complex · an experimental structure of the same protein · chain A against J, TM-score 0.18
- 7EGP · The structure of SWI/SNF-nucleosome complex · an experimental structure of the same protein · chain A against J, TM-score 0.18
- 7EGP · The structure of SWI/SNF-nucleosome complex · an experimental structure of the same protein · chain A against J, TM-score 0.18
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43554
- Elsewhere: UniProt P43554 · AlphaFold DB P43554
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.