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AlphaFold monomer V2.0 prediction for SWI/SNF global transcription activator complex subunit SWP82 (P43554)

Analyse AlphaFold monomer V2.0 prediction for SWI/SNF global transcription activator… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P43554
Type
protein
Length
623 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9188600a0FCa2914254C94299b1bd9721Bc4D500
Molecule
SWI/SNF global transcription activator complex subunit SWP82
UniProt
P43554
Pockets
10 · best druggability 0.67

Structure

1 distinct chain · 35% helix, 8% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASWI/SNF global transcription activator complex subunit SWP82protein62335% helix, 8% strandP43554

Pockets

10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17380.670.7558empty
22070.610.8225empty
31840.570.8019empty
43510.530.7345empty
51310.490.7932empty

Compared structures

  • 7C4J · Cryo-EM structure of the yeast SWI/SNF complex in a nucleosome free state · an experimental structure of the same protein · chain A against E, TM-score 0.21
  • 7C4J · Cryo-EM structure of the yeast Swi/Snf complex in a nucleosome free state · an experimental structure of the same protein · chain A against E, TM-score 0.21
  • 7EGM · The srm module of SWI/SNF-nucleosome complex · an experimental structure of the same protein · chain A against J, TM-score 0.18
  • 7EGM · The SRM module of SWI/SNF-nucleosome complex · an experimental structure of the same protein · chain A against J, TM-score 0.18
  • 7EGP · The structure of SWI/SNF-nucleosome complex · an experimental structure of the same protein · chain A against J, TM-score 0.18
  • 7EGP · The structure of SWI/SNF-nucleosome complex · an experimental structure of the same protein · chain A against J, TM-score 0.18

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