MolNFT v1 · #440544 · protein

AlphaFold monomer V2.0 prediction for succinate--CoA ligase [ADP/GDP- forming] subunit alpha, mitochondrial (P53597)

P53597 · Succinate--CoA ligase [ADP/GDP-forming] subunit alpha…: “AlphaFold monomer V2.0 prediction for succinate--CoA ligase [ADP/GDP- forming] subunit alpha, mitochondrial…”. 1 pocket (best druggability 0.46). MolNFT v1 #440544 on…

Accession: P53597
Type: protein
Length: 346 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7FDF8b382C6a36A8772D1A265E8e480c7DF0A9C1
Molecule: Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
UniProt: P53597
Pockets: 1 · best druggability 0.46

Structure

1 distinct chain · 33% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial	protein	346	33% helix, 19% strand	P53597

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	124	0.46	0.78	30	empty

Compared structures

6WCV · Tartryl-CoA bound to human GTP-specific succinyl-CoA synthetase · an experimental structure of the same protein · chain A against A, TM-score 0.88
6G4Q · Structure of human ADP-forming succinyl-CoA ligase complex SUCLG1- SUCLA2 · an experimental structure of the same protein · chain A against A, TM-score 0.88
7MSR · Human E105Qa GTP-specific succinyl-CoA synthetase complexed with succinyl-phosphate… · an experimental structure of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P53597
Elsewhere: UniProt P53597 · AlphaFold DB P53597

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