AlphaFold monomer V2.0 prediction for cst complex subunit STN1 (Q9H668)

Structure

1 distinct chain · 44% helix, 21% strand (DSSP).

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 8D0B · Human cst-DNA polymerase ALPHA/PRIMASE preinitiation complex bound to 4XTEL-foldback… · an experimental structure of the same protein · chain A against B, TM-score 0.56
• 8D0B · Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback… · an experimental structure of the same protein · chain A against B, TM-score 0.56
• 8D0K · Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback… · an experimental structure of the same protein · chain A against B, TM-score 0.55
• 8D0K · Human cst-DNA polymerase ALPHA/PRIMASE preinitiation complex bound to 4XTEL-foldback… · an experimental structure of the same protein · chain A against B, TM-score 0.55
• 8SOJ · Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the absence of telomeric ssDNA · an experimental structure of the same protein · chain A against B, TM-score 0.47
• 8SOK · Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the presence of telomeric ssDNA · an experimental structure of the same protein · chain A against B, TM-score 0.47
• 4JQF · Structure of the C-terminal domain of human telomeric Stn1 · an experimental structure of the same protein · chain A against A, TM-score 0.45
• 4JQF · Structure of the C-terminal domain of human telomeric STN1 · an experimental structure of the same protein · chain A against A, TM-score 0.45
• 6W6W · Cryo-EM structure of CST bound to telomeric single-stranded DNA · an experimental structure of the same protein · chain A against C, TM-score 0.43
• 6W6W · Cryo-EM structure of cst bound to telomeric single-stranded DNA · an experimental structure of the same protein · chain A against C, TM-score 0.43
• 7U5C · Cryo-EM structure of human cst bound to DNA polymerase alpha-primase in a recruitment… · an experimental structure of the same protein · chain A against F, TM-score 0.38
• 7U5C · Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment… · an experimental structure of the same protein · chain A against F, TM-score 0.38

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9H668
• Elsewhere: UniProt Q9H668 · AlphaFold DB Q9H668