GL1X · GenesisL1 explorer

MolNFT v1 · #436695 · protein

AlphaFold monomer V2.0 prediction for signal recognition particle 54 kda protein (P61010)

P61010: “AlphaFold monomer V2.0 prediction for signal recognition particle 54 kda protein (P61010)”. 6 pockets (best druggability 0.76). MolNFT v1 #436695 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P61010
Type
protein
Length
504 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x70189663D9D82ce5dB28B4Fdc41ba0b8D3788BD3
Molecule
Signal recognition particle 54 kda protein
UniProt
P61010
Pockets
6 · best druggability 0.76

Structure

1 distinct chain · 59% helix, 8% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASignal recognition particle 54 kda proteinprotein50459% helix, 8% strandP61010

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18130.760.8065empty
2900.420.7925empty
31090.410.7624empty
4910.360.7417empty
5830.350.7412empty

Compared structures

  • 4UE5 · Structural basis for targeting and elongation arrest of bacillus signal recognition… · an experimental structure of the same protein · chain A against D, TM-score 0.74
  • 4UE5 · Structural basis for targeting and elongation arrest of Bacillus signal recognition… · an experimental structure of the same protein · chain A against D, TM-score 0.74
  • 2J37 · Model of mammalian srp bound to 80S rncs · an experimental structure of the same protein · chain A against W, TM-score 0.73
  • 2J37 · Model of mammalian srp bound to 80S rncs · an experimental structure of the same protein · chain A against W, TM-score 0.73
  • 6R6G · Structure of XBP1u-paused ribosome nascent chain complex with SRP. · an experimental structure of the same protein · chain A against AB, TM-score 0.72
  • 7OBQ · SRP-SR at the distal site conformation · an experimental structure of the same protein · chain A against x, TM-score 0.53
  • 7OBQ · Srp-sr at the distal site conformation · an experimental structure of the same protein · chain A against x, TM-score 0.53
  • 6FRK · Structure of a prehandover mammalian ribosomal SRP and SRP receptor targeting complex · an experimental structure of the same protein · chain A against x, TM-score 0.51
  • 2GO5 · Structure of signal recognition particle receptor (SR) in complex with signal recognition… · an experimental structure of the same protein · chain A against W, TM-score 0.20
  • 2GO5 · Structure of signal recognition particle receptor (sr) in complex with signal recognition… · an experimental structure of the same protein · chain A against W, TM-score 0.20

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