MolNFT v1 · #432735 · protein
AlphaFold monomer V2.0 prediction for somatotropin (P01241)
P01241: “AlphaFold monomer V2.0 prediction for somatotropin (P01241)”. 2 pockets (best druggability 0.31). MolNFT v1 #432735 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P01241
- Type
- protein
- Length
- 217 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x2bF85003001845aBBb5157E430B59466805f04aE
- Molecule
- Somatotropin
- UniProt
- P01241
- Pockets
- 2 · best druggability 0.31
Structure
1 distinct chain · 68% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Somatotropin | protein | 217 | 68% helix, 0% strand | P01241 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.31 | 0.77 | 16 | empty |
| 2 | 62 | 0.26 | 0.72 | 12 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1BP3 · The xray structure of a growth hormone-prolactin receptor complex · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 1BP3 · The xray structure of a growth hormone-prolactin receptor complex · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 3HHR · Human growth hormone and extracellular domain of its receptor: crystal structure of the… · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 3HHR · Human growth hormone and extracellular domain of its receptor: crystal structure of the… · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 1HWG · 1:2 complex of human growth hormone with its soluble binding protein · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 1HWG · 1:2 complex of human growth hormone with its soluble binding protein · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 1HWH · 1:1 complex of human growth hormone mutant G120R with its soluble binding protein · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 1HWH · 1:1 complex of human growth hormone mutant G120R with its soluble binding protein · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 1A22 · Human growth hormone bound to single receptor · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 1A22 · Human growth hormone bound to single receptor · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 1HGU · Human growth hormone · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 1HGU · Human growth hormone · an experimental structure of the same protein · chain A against A, TM-score 0.72
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01241
- Elsewhere: UniProt P01241 · AlphaFold DB P01241
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