MolNFT v1 · #431207 · protein
AlphaFold monomer V2.0 prediction for structural maintenance of chromosomes flexible hinge domain-containing protein 1 (Q6P5D8)
Q6P5D8: “AlphaFold monomer V2.0 prediction for structural maintenance of chromosomes flexible hinge domain-containing…”. 17 pockets (best druggability 0.78). MolNFT v1 #431207 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6P5D8
- Type
- protein
- Length
- 2,007 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x05Dc5F64ec3DDC2CEdF9ba8CD7b6b5056bB42D27
- Molecule
- Structural maintenance of chromosomes flexible hinge domain-containing protein 1
- UniProt
- Q6P5D8
- Pockets
- 17 · best druggability 0.78
Structure
1 distinct chain · 19% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 | protein | 2007 | 19% helix, 34% strand | Q6P5D8 |
Pockets
17 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 714 | 0.78 | 0.83 | 75 | empty |
| 2 | 65 | 0.67 | 0.94 | 25 | empty |
| 3 | 419 | 0.59 | 0.75 | 57 | empty |
| 4 | 432 | 0.56 | 0.73 | 48 | empty |
| 5 | 219 | 0.53 | 0.77 | 41 | empty |
Compared structures
- 6N64 · Crystal structure of mouse SMCHD1 hinge domain · an experimental structure of the same protein · chain A against B, TM-score 0.07
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6P5D8
- Elsewhere: UniProt Q6P5D8 · AlphaFold DB Q6P5D8
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