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AlphaFold monomer V2.0 prediction for structural maintenance of chromosomes flexible hinge domain-containing protein 1 (Q6P5D8)

Analyse AlphaFold monomer V2.0 prediction for structural maintenance of chromosomes… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q6P5D8
Type: protein
Length: 2,007 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x05Dc5F64ec3DDC2CEdF9ba8CD7b6b5056bB42D27
Molecule: Structural maintenance of chromosomes flexible hinge domain-containing protein 1
UniProt: Q6P5D8
Pockets: 17 · best druggability 0.78

Structure

1 distinct chain · 19% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Structural maintenance of chromosomes flexible hinge domain-containing protein 1	protein	2007	19% helix, 34% strand	Q6P5D8

Pockets

17 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	714	0.78	0.83	75	empty
2	65	0.67	0.94	25	empty
3	419	0.59	0.75	57	empty
4	432	0.56	0.73	48	empty
5	219	0.53	0.77	41	empty

Compared structures

6N64 · Crystal structure of mouse SMCHD1 hinge domain · an experimental structure of the same protein · chain A against B, TM-score 0.07
6N64 · Crystal structure of mouse SMCHD1 hinge domain · an experimental structure of the same protein · chain A against B, TM-score 0.07

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6P5D8
Elsewhere: UniProt Q6P5D8 · AlphaFold DB Q6P5D8

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