GL1X · GenesisL1 explorer

MolNFT v1 · #430927 · protein

AlphaFold monomer V2.0 prediction for chromosome partition protein smc (P51834)

P51834: “AlphaFold monomer V2.0 prediction for chromosome partition protein smc (P51834)”. 7 pockets (best druggability 0.52). MolNFT v1 #430927 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P51834
Type
protein
Length
1,186 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xd1A2963012bEcbC7A8f505464439Ab678C48936f
Molecule
Chromosome partition protein smc
UniProt
P51834
Pockets
7 · best druggability 0.52

Structure

1 distinct chain · 67% helix, 10% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AChromosome partition protein smcprotein118667% helix, 10% strandP51834

Pockets

7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11170.520.8225empty
2740.480.8320empty
31390.460.7728empty
41520.420.7421empty
5850.380.7712empty

Compared structures

  • 5XG3 · Crystal structure of the atpgs-engaged smc head domain with an extended coiled coil bound… · an experimental structure of the same protein · chain A against B, TM-score 0.29
  • 3ZGX · Crystal structure of the kleisin-N SMC interface in prokaryotic condensin · an experimental structure of the same protein · chain A against B, TM-score 0.25
  • 3ZGX · Crystal structure of the kleisin-N smc interface in prokaryotic condensin · an experimental structure of the same protein · chain A against B, TM-score 0.25
  • 5NNV · Structure of a bacillus subtilis smc coiled coil middle fragment · an experimental structure of the same protein · chain A against D, TM-score 0.18
  • 5H67 · Crystal structure of the bacillus subtilis smc head domain complexed with the cognate… · an experimental structure of the same protein · chain A against A, TM-score 0.16
  • 5H66 · Crystal structure of the bacillus subtilis smc head domain complexed with the cognate… · an experimental structure of the same protein · chain A against A, TM-score 0.15

Analyse

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