GL1X · GenesisL1 explorer

MolNFT v1 · #430310 · protein

AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor SLU7 (Q02775)

Q02775: “AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor SLU7 (Q02775)”. 3 pockets (best druggability 0.34). MolNFT v1 #430310 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q02775
Type
protein
Length
382 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xEa58c7534E5701aA8370E0fAEb19b7e14653e69c
Molecule
Pre-mRNA-splicing factor SLU7
UniProt
Q02775
Pockets
3 · best druggability 0.34

Structure

1 distinct chain · 38% helix, 6% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APre-mRNA-splicing factor SLU7protein38238% helix, 6% strandQ02775

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1950.340.7417empty
2590.330.7713empty
3630.320.7613empty

Compared structures

  • 6BK8 · S. cerevisiae spliceosomal post-catalytic P complex · an experimental structure of the same protein · chain A against O, TM-score 0.43
  • 6EXN · Post-catalytic P complex spliceosome with 3' splice site docked · an experimental structure of the same protein · chain A against c, TM-score 0.40
  • 6EXN · Post-catalytic P complex spliceosome with 3' splice site docked · an experimental structure of the same protein · chain A against c, TM-score 0.40
  • 5MPS · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against c, TM-score 0.20
  • 5MQ0 · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against c, TM-score 0.20
  • 5MQ0 · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against c, TM-score 0.20
  • 5YLZ · Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6… · an experimental structure of the same protein · chain A against V, TM-score 0.18
  • 5YLZ · Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6… · an experimental structure of the same protein · chain A against V, TM-score 0.18

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