MolNFT v1 · #430202 · protein
AlphaFold monomer V2.0 prediction for calcium-activated potassium channel slowpoke (Q03720)
Q03720: “AlphaFold monomer V2.0 prediction for calcium-activated potassium channel slowpoke (Q03720)”. 16 pockets (best druggability 0.80). MolNFT v1 #430202 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q03720
- Type
- protein
- Length
- 1,200 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9B800d48d871ED865b4dc8330EC3e1EAD024B41F
- Molecule
- Calcium-activated potassium channel slowpoke
- UniProt
- Q03720
- Pockets
- 16 · best druggability 0.80
Structure
1 distinct chain · 37% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Calcium-activated potassium channel slowpoke | protein | 1200 | 37% helix, 11% strand | Q03720 |
Pockets
16 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 184 | 0.80 | 0.94 | 24 | empty |
| 2 | 530 | 0.71 | 0.80 | 59 | empty |
| 3 | 405 | 0.68 | 0.80 | 49 | empty |
| 4 | 554 | 0.66 | 0.77 | 58 | empty |
| 5 | 446 | 0.64 | 0.77 | 32 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7PXG · Verruculogen-bound Drosophila Slo channel · an experimental structure of the same protein · chain A against C, TM-score 0.72
- 7PXG · Verruculogen-bound drosophila slo channel · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 7PXH · Emodepside-bound Drosophila Slo channel · an experimental structure of the same protein · chain A against C, TM-score 0.72
- 7PXH · Emodepside-bound drosophila slo channel · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 7PXE · Ca2+ bound Drosophila Slo channel · an experimental structure of the same protein · chain A against D, TM-score 0.72
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q03720
- Elsewhere: UniProt Q03720 · AlphaFold DB Q03720
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.