AlphaFold monomer V2.0 prediction for leucine-rich repeat protein shoc-2 (Q9UQ13)

Structure

1 distinct chain · 20% helix, 10% strand (DSSP).

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 7SD1 · Crystal structure of SHOC2 · an experimental structure of the same protein · chain A against A, TM-score 0.85
• 7TYG · Structure of the human leucine rich repeat protein SHOC2, residues 80- 582 · an experimental structure of the same protein · chain A against A, TM-score 0.84
• 7T7A · Crystal Structure of Human SHOC2: A Leucine-Rich Repeat Protein · an experimental structure of the same protein · chain A against B, TM-score 0.84
• 7T7A · Crystal structure of human SHOC2: a leucine-rich repeat protein · an experimental structure of the same protein · chain A against B, TM-score 0.84
• 7TXH · Human mras Q71R in complex with human SHOC2 lrr domain M173I and human PP1CA · an experimental structure of the same protein · chain A against E, TM-score 0.84
• 7UPI · Cryo-EM structure of SHOC2-PP1C-mras holophosphatase complex · an experimental structure of the same protein · chain A against C, TM-score 0.83
• 7TVF · Crystal structure of the SHOC2-mras-PP1CA (smp) complex to a resolution of 2.17 ångström · an experimental structure of the same protein · chain A against D, TM-score 0.83

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9UQ13
• Elsewhere: UniProt Q9UQ13 · AlphaFold DB Q9UQ13