Research workbench
AlphaFold monomer V2.0 prediction for leucine-rich repeat protein shoc-2 (Q9UQ13)
Analyse AlphaFold monomer V2.0 prediction for leucine-rich repeat protein shoc-2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9UQ13
- Type
- protein
- Length
- 582 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xD078c9CbF2729549ADF337b0f5AB69B760a74D2e
- Molecule
- Leucine-rich repeat protein shoc-2
- UniProt
- Q9UQ13
- Pockets
- 2 · best druggability 0.48
Structure
1 distinct chain · 20% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Leucine-rich repeat protein shoc-2 | protein | 582 | 20% helix, 10% strand | Q9UQ13 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.48 | 0.83 | 20 | empty |
| 2 | 74 | 0.28 | 0.73 | 17 | empty |
Compared structures
- 7SD1 · Crystal structure of SHOC2 · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 7TYG · Structure of the human leucine rich repeat protein SHOC2, residues 80- 582 · an experimental structure of the same protein · chain A against A, TM-score 0.84
- 7T7A · Crystal Structure of Human SHOC2: A Leucine-Rich Repeat Protein · an experimental structure of the same protein · chain A against B, TM-score 0.84
- 7T7A · Crystal structure of human SHOC2: a leucine-rich repeat protein · an experimental structure of the same protein · chain A against B, TM-score 0.84
- 7TXH · Human mras Q71R in complex with human SHOC2 lrr domain M173I and human PP1CA · an experimental structure of the same protein · chain A against E, TM-score 0.84
- 7UPI · Cryo-EM structure of SHOC2-PP1c-MRAS holophosphatase complex · an experimental structure of the same protein · chain A against C, TM-score 0.83
- 7UPI · Cryo-EM structure of SHOC2-PP1C-mras holophosphatase complex · an experimental structure of the same protein · chain A against C, TM-score 0.83
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UQ13
- Elsewhere: UniProt Q9UQ13 · AlphaFold DB Q9UQ13
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