MolNFT v1 · #427058 · protein
AlphaFold monomer V2.0 prediction for splicing factor 3B subunit 4 (Q15427)
Q15427: “AlphaFold monomer V2.0 prediction for splicing factor 3B subunit 4 (Q15427)”. 1 pocket (best druggability 0.51). MolNFT v1 #427058 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q15427
- Type
- protein
- Length
- 424 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1deF5d0757faedfe2A626225e579ACe5e2e425d2
- Molecule
- Splicing factor 3B subunit 4
- UniProt
- Q15427
- Pockets
- 1 · best druggability 0.51
Structure
1 distinct chain · 13% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Splicing factor 3B subunit 4 | protein | 424 | 13% helix, 13% strand | Q15427 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 221 | 0.51 | 0.76 | 32 | empty |
Compared structures
- 8I0P · The cryo-EM structure of human pre-Bact complex · an experimental structure of the same protein · chain A against 4, TM-score 0.30
- 8I0R · The cryo-EM structure of human Bact-I complex · an experimental structure of the same protein · chain A against 4, TM-score 0.29
- 8I0T · The cryo-EM structure of human Bact-III complex · an experimental structure of the same protein · chain A against 4, TM-score 0.29
- 8I0V · The cryo-EM structure of human post-Bact complex · an experimental structure of the same protein · chain A against 4, TM-score 0.27
- 8I0S · The cryo-EM structure of human Bact-II complex · an experimental structure of the same protein · chain A against 4, TM-score 0.26
- 8I0U · The cryo-EM structure of human Bact-IV complex · an experimental structure of the same protein · chain A against 4, TM-score 0.23
- 8HK1 · The cryo-EM structure of human pre-17S U2 snRNP · an experimental structure of the same protein · chain A against 4, TM-score 0.22
- 7EVO · The cryo-EM structure of the human 17S U2 snrnp · an experimental structure of the same protein · chain A against 4, TM-score 0.22
- 7EVO · The cryo-EM structure of the human 17S U2 snRNP · an experimental structure of the same protein · chain A against 4, TM-score 0.22
- 7VPX · The cryo-EM structure of the human pre-A complex · an experimental structure of the same protein · chain A against 4, TM-score 0.22
- 6Y53 · Human 17S U2 snrnp low resolution part · an experimental structure of the same protein · chain A against o, TM-score 0.22
- 6Y53 · human 17S U2 snRNP low resolution part · an experimental structure of the same protein · chain A against o, TM-score 0.22
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15427
- Elsewhere: UniProt Q15427 · AlphaFold DB Q15427
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