MolNFT v1 · #426915 · protein
AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase SETD7 (Q8WTS6)
Q8WTS6: “AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase SETD7 (Q8WTS6)”. 2 pockets (best druggability 0.47). MolNFT v1 #426915 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8WTS6
- Type
- protein
- Length
- 366 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x54E712e282c590D9A20961451A63f1380e0a3dD4
- Molecule
- Histone-lysine N-methyltransferase SETD7
- UniProt
- Q8WTS6
- Pockets
- 2 · best druggability 0.47
Structure
1 distinct chain · 9% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Histone-lysine N-methyltransferase SETD7 | protein | 366 | 9% helix, 47% strand | Q8WTS6 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 144 | 0.47 | 0.78 | 25 | empty |
| 2 | 158 | 0.43 | 0.75 | 29 | empty |
Compared structures
- 1N6C · Structure of SET7/9 · an experimental structure of the same protein · chain A against A, TM-score 0.76
- 1N6C · Structure of SET7/9 · an experimental structure of the same protein · chain A against A, TM-score 0.76
- 1H3I · Crystal structure of the Histone Methyltransferase SET7/9 · an experimental structure of the same protein · chain A against A, TM-score 0.76
- 1H3I · Crystal structure of the histone methyltransferase SET7/9 · an experimental structure of the same protein · chain A against A, TM-score 0.76
- 1MT6 · Structure of histone H3 K4-specific methyltransferase SET7/9 with AdoHcy · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 1MT6 · Structure of histone H3 K4-specific methyltransferase SET7/9 with adohcy · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 1MUF · Structure of histone H3 K4-specific methyltransferase SET7/9 · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 1MUF · Structure of histone H3 K4-specific methyltransferase SET7/9 · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 1XQH · Crystal structure of a ternary complex of the methyltransferase SET9 (also known as… · an experimental structure of the same protein · chain A against A, TM-score 0.68
- 1XQH · Crystal structure of a ternary complex of the methyltransferase SET9 (also known as… · an experimental structure of the same protein · chain A against A, TM-score 0.68
- 1O9S · Crystal structure of a ternary complex of the human histone methyltransferase SET7/9 · an experimental structure of the same protein · chain A against A, TM-score 0.68
- 1O9S · Crystal structure of a ternary complex of the human histone methyltransferase SET7/9 · an experimental structure of the same protein · chain A against A, TM-score 0.68
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8WTS6
- Elsewhere: UniProt Q8WTS6 · AlphaFold DB Q8WTS6
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