AlphaFold monomer V2.0 prediction for streptavidin (P22629)

Structure

1 distinct chain · 17% helix, 37% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 9CSU · Streptavidin-E101Q-S112Y-K121A bound to Cu(II)-biotin-ethyl-dipicolylamine cofactor · an experimental structure of the same protein · chain A against A, TM-score 0.67
• 1N9M · Streptavidin Mutant S27A with Biotin at 1.6A Resolution · an experimental structure of the same protein · chain A against C, TM-score 0.67
• 1I9H · Core streptavidin-bna complex · an experimental structure of the same protein · chain A against B, TM-score 0.67
• 5CSE · Streptavidin-S112Y-K121E Complexed with Palladium-Containing Biotin Ligand · an experimental structure of the same protein · chain A against B, TM-score 0.66
• 6AUE · Artificial Metalloproteins Containing a Co4O4 Active Site - 2xm-S112Y-b · an experimental structure of the same protein · chain A against A, TM-score 0.66
• 1SRI · Structure-based design of synthetic azobenzene ligands for streptavidin · an experimental structure of the same protein · chain A against B, TM-score 0.66
• 1STP · Structural origins of high-affinity biotin binding to streptavidin · an experimental structure of the same protein · chain A against A, TM-score 0.66
• 1SLF · Apostreptavidin, pH 5.6, two molecules of (SO4)2 bound at the biotin binding site · an experimental structure of the same protein · chain A against B, TM-score 0.65
• 1NBX · Streptavidin Mutant Y43A at 1.70A Resolution · an experimental structure of the same protein · chain A against A, TM-score 0.65
• 1SWA · Apo-core-streptavidin at pH 4.5 · an experimental structure of the same protein · chain A against A, TM-score 0.65

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P22629
• Elsewhere: UniProt P22629 · AlphaFold DB P22629