MolNFT v1 · #418538 · protein

AlphaFold monomer V2.0 prediction for thiamine transporter 2 (Q9BZV2)

Q9BZV2: “AlphaFold monomer V2.0 prediction for thiamine transporter 2 (Q9BZV2)”. 1 pocket (best druggability 0.87). MolNFT v1 #418538 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9BZV2
Type: protein
Length: 496 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xEfeF22Cb92c4cdFf0004010904498915700e52C5
Molecule: Thiamine transporter 2
UniProt: Q9BZV2
Pockets: 1 · best druggability 0.87

Structure

1 distinct chain · 69% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Thiamine transporter 2	protein	496	69% helix, 0% strand	Q9BZV2

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	996	0.87	0.88	76	empty

Compared structures

8S5W · Cryo-EM structure of fedratinib-bound human SLC19A3 in inward-open state · an experimental structure of the same protein · chain A against A, TM-score 0.76
8S5U · Cryo-EM structure of thiamine-bound human SLC19A3 in outward-open state · an experimental structure of the same protein · chain A against A, TM-score 0.63

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9BZV2
Elsewhere: UniProt Q9BZV2 · AlphaFold DB Q9BZV2

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