MolNFT v1 · #386696 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (O52760)
O52760: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (O52760)”. 2 pockets (best druggability 0.41). MolNFT v1 #386696 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O52760
- Type
- protein
- Length
- 333 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x27e67Efe562B17F05415cb640674a08713e14067
- Molecule
- DNA-directed RNA polymerase subunit alpha
- UniProt
- O52760
- Pockets
- 2 · best druggability 0.41
Structure
1 distinct chain · 30% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit alpha | protein | 333 | 30% helix, 30% strand | O52760 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 106 | 0.41 | 0.75 | 23 | empty |
| 2 | 59 | 0.38 | 0.79 | 12 | empty |
Compared structures
- 7XL4 · Cryo-EM structure of pseudomonas aeruginosa rnap sigmas holoenzyme complexes with… · an experimental structure of the same protein · chain A against A, TM-score 0.62
- 7XL3 · Cryo-EM structure of pseudomonas aeruginosa rnap sigmas holoenzyme complexes with… · an experimental structure of the same protein · chain A against A, TM-score 0.61
- 7XYA · The cryo-EM structure of an alpa-loading complex · an experimental structure of the same protein · chain A against A, TM-score 0.61
- 7XYB · The cryo-EM structure of an alpa-loaded complex · an experimental structure of the same protein · chain A against A, TM-score 0.60
- 7VF9 · Cryo-EM structure of pseudomonas aeruginosa rnap sigmas holoenzyme complexes · an experimental structure of the same protein · chain A against A, TM-score 0.60
- 7F0R · Cryo-EM structure of pseudomonas aeruginosa suta transcription activation complex · an experimental structure of the same protein · chain A against A, TM-score 0.59
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O52760
- Elsewhere: UniProt O52760 · AlphaFold DB O52760
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.