UniProt O52760
DNA-directed RNA polymerase subunit alpha (O52760)
DNA-directed RNA polymerase subunit alpha (UniProt O52760), EC 2.7.7.6: 11 experimental structures and 1 predicted model on GenesisL1, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O52760
- Protein
- DNA-directed RNA polymerase subunit alpha
- EC
- 2.7.7.6
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 26 · 5 records with a druggable one
Structures
12 records of O52760 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7F0R | Cryo-EM structure of Pseudomonas aeruginosa SutA transcription activation complex | electron microscopy | A, B | — | 6 (best 0.86) |
| 7F0R | Cryo-EM structure of pseudomonas aeruginosa suta transcription activation complex | electron microscopy | A, B | — | — |
| 7VF9 | Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes | electron microscopy | A, B | — | 5 (best 0.83) |
| 7VF9 | Cryo-EM structure of pseudomonas aeruginosa rnap sigmas holoenzyme complexes | electron microscopy | A, B | — | — |
| 7XL3 | Cryo-EM structure of pseudomonas aeruginosa rnap sigmas holoenzyme complexes with transcription… | electron microscopy | A, B | — | — |
| 7XL4 | Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription… | electron microscopy | A, B | — | 6 (best 0.84) |
| 7XL4 | Cryo-EM structure of pseudomonas aeruginosa rnap sigmas holoenzyme complexes with transcription… | electron microscopy | A, B | — | — |
| 7XYA | The cryo-EM structure of an AlpA-loading complex | electron microscopy | A, B | — | 3 (best 0.84) |
| 7XYA | The cryo-EM structure of an alpa-loading complex | electron microscopy | A, B | — | — |
| 7XYB | The cryo-EM structure of an AlpA-loaded complex | electron microscopy | A, B | — | 4 (best 0.83) |
| 7XYB | The cryo-EM structure of an alpa-loaded complex | electron microscopy | A, B | — | — |
| O52760 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (O52760) | predicted | A | — | 2 (best 0.41) |
Experiment against prediction
- 7XYA chain A against the predicted model O52760: TM-score 0.92, RMSD 1.77 Å
- 7XYA chain A against the predicted model O52760: TM-score 0.92, RMSD 1.77 Å
- 7XYB chain A against the predicted model O52760: TM-score 0.91, RMSD 1.83 Å
- 7XYB chain A against the predicted model O52760: TM-score 0.91, RMSD 1.83 Å
- 7VF9 chain A against the predicted model O52760: TM-score 0.91, RMSD 1.84 Å
- 7VF9 chain A against the predicted model O52760: TM-score 0.91, RMSD 1.84 Å
- 7XL3 chain A against the predicted model O52760: TM-score 0.90, RMSD 1.92 Å
- 7XL4 chain A against the predicted model O52760: TM-score 0.90, RMSD 2.08 Å
- 7XL4 chain A against the predicted model O52760: TM-score 0.90, RMSD 2.08 Å
- 7XYB chain B against the predicted model O52760: TM-score 0.89, RMSD 2.01 Å
Elsewhere
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