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MolNFT v1 · #385919 · protein

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit L (Q8U4N1)

Q8U4N1: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit L (Q8U4N1)”. 1 pocket (best druggability 0.31). MolNFT v1 #385919 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q8U4N1
Type
protein
Length
95 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xdbAF8966CCe723d803E73D904c686C788374F84D
Molecule
DNA-directed RNA polymerase subunit L
UniProt
Q8U4N1
Pockets
1 · best druggability 0.31

Structure

1 distinct chain · 42% helix, 29% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA-directed RNA polymerase subunit Lprotein9542% helix, 29% strandQ8U4N1

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1510.310.7512empty

Compared structures

  • 8RBO · Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp… · an experimental structure of the same protein · chain A against L, TM-score 0.98
  • 8P2I · Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp… · an experimental structure of the same protein · chain A against L, TM-score 0.98
  • 8CRO · Cryo-EM structure of Pyrococcus furiosus transcription elongation complex · an experimental structure of the same protein · chain A against L, TM-score 0.97
  • 8ORQ · Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase open clamp conformation · an experimental structure of the same protein · chain A against L, TM-score 0.97
  • 8OKI · Cryo-EM structure of Pyrococcus furiosus transcription elongation complex bound to Spt4/5 · an experimental structure of the same protein · chain A against L, TM-score 0.96

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