UniProt Q8U4N1

DNA-directed RNA polymerase subunit Rpo11 (Q8U4N1)

DNA-directed RNA polymerase subunit Rpo11 (UniProt Q8U4N1), EC 2.7.7.6: 5 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q8U4N1
Protein: DNA-directed RNA polymerase subunit Rpo11
EC: 2.7.7.6
Experimental structures: 5
Predicted models: 1
Pockets: 7 · 5 records with a druggable one

Structures

6 records of Q8U4N1 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
8CRO	Cryo-EM structure of Pyrococcus furiosus transcription elongation complex	electron microscopy	L	—	2 (best 0.74)
8OKI	Cryo-EM structure of Pyrococcus furiosus transcription elongation complex bound to Spt4/5	electron microscopy	L	—	1 (best 0.79)
8ORQ	Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase open clamp conformation	electron microscopy	L	—	1 (best 0.75)
8P2I	Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation with…	electron microscopy	L	—	1 (best 0.79)
8RBO	Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation	electron microscopy	L	—	1 (best 0.77)
Q8U4N1	AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit L (Q8U4N1)	predicted	A	—	1 (best 0.31)

Experiment against prediction

8RBO chain L against the predicted model Q8U4N1: TM-score 0.99, RMSD 0.43 Å
8P2I chain L against the predicted model Q8U4N1: TM-score 0.99, RMSD 0.43 Å
8CRO chain L against the predicted model Q8U4N1: TM-score 0.98, RMSD 0.45 Å
8ORQ chain L against the predicted model Q8U4N1: TM-score 0.98, RMSD 0.45 Å
8OKI chain L against the predicted model Q8U4N1: TM-score 0.97, RMSD 0.60 Å

Elsewhere

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