MolNFT v1 · #385009 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB4 (O15514)
O15514: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB4 (O15514)”. 1 pocket (best druggability 0.27). MolNFT v1 #385009 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O15514
- Type
- protein
- Length
- 142 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
- Molecule
- DNA-directed RNA polymerase II subunit RPB4
- UniProt
- O15514
- Pockets
- 1 · best druggability 0.27
Structure
1 distinct chain · 58% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase II subunit RPB4 | protein | 142 | 58% helix, 1% strand | O15514 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 55 | 0.27 | 0.73 | 13 | empty |
Compared structures
- 2C35 · Subunits Rpb4 and Rpb7 of human RNA polymerase II · an experimental structure of the same protein · chain A against E, TM-score 0.84
- 2C35 · Subunits RPB4 and RPB7 of human RNA polymerase II · an experimental structure of the same protein · chain A against E, TM-score 0.84
- 5IY9 · Human holo-pic in the initial transcribing state (no iis) · an experimental structure of the same protein · chain A against D, TM-score 0.84
- 5IY9 · Human holo-PIC in the initial transcribing state (no IIS) · an experimental structure of the same protein · chain A against D, TM-score 0.84
- 5IYD · Human core-pic in the initial transcribing state (no iis) · an experimental structure of the same protein · chain A against D, TM-score 0.84
- 5IYD · Human core-PIC in the initial transcribing state (no IIS) · an experimental structure of the same protein · chain A against D, TM-score 0.84
- 5IY8 · Human holo-pic in the initial transcribing state · an experimental structure of the same protein · chain A against D, TM-score 0.83
- 5IYC · Human core-pic in the initial transcribing state · an experimental structure of the same protein · chain A against D, TM-score 0.83
- 5IYC · Human core-PIC in the initial transcribing state · an experimental structure of the same protein · chain A against D, TM-score 0.83
- 5IYA · Human core-PIC in the closed state · an experimental structure of the same protein · chain A against D, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O15514
- Elsewhere: UniProt O15514 · AlphaFold DB O15514
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