GL1X · GenesisL1 explorer

Research workbench

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB4 (O15514)

Analyse AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
O15514
Type
protein
Length
142 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
Molecule
DNA-directed RNA polymerase II subunit RPB4
UniProt
O15514
Pockets
1 · best druggability 0.27

Structure

1 distinct chain · 58% helix, 1% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA-directed RNA polymerase II subunit RPB4protein14258% helix, 1% strandO15514

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1550.270.7313empty

Compared structures

  • 2C35 · Subunits Rpb4 and Rpb7 of human RNA polymerase II · an experimental structure of the same protein · chain A against E, TM-score 0.84
  • 2C35 · Subunits RPB4 and RPB7 of human RNA polymerase II · an experimental structure of the same protein · chain A against E, TM-score 0.84
  • 7LBM · Structure of the human Mediator-bound transcription pre-initiation complex · an experimental structure of the same protein · chain A against D, TM-score 0.84
  • 5IYD · Human core-PIC in the initial transcribing state (no IIS) · an experimental structure of the same protein · chain A against D, TM-score 0.84
  • 5IY9 · Human holo-pic in the initial transcribing state (no iis) · an experimental structure of the same protein · chain A against D, TM-score 0.84
  • 5IY9 · Human holo-PIC in the initial transcribing state (no IIS) · an experimental structure of the same protein · chain A against D, TM-score 0.84
  • 5IYD · Human core-pic in the initial transcribing state (no iis) · an experimental structure of the same protein · chain A against D, TM-score 0.84
  • 5IY8 · Human holo-pic in the initial transcribing state · an experimental structure of the same protein · chain A against D, TM-score 0.83
  • 5IY8 · Human holo-PIC in the initial transcribing state · an experimental structure of the same protein · chain A against D, TM-score 0.83
  • 5IYC · Human core-PIC in the initial transcribing state · an experimental structure of the same protein · chain A against D, TM-score 0.83

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.