MolNFT v1 · #384950 · protein
AlphaFold monomer V2.0 prediction for RNA polymerase II-associated protein 3 (Q9H6T3)
Q9H6T3: “AlphaFold monomer V2.0 prediction for RNA polymerase II-associated protein 3 (Q9H6T3)”. 3 pockets (best druggability 0.59). MolNFT v1 #384950 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9H6T3
- Type
- protein
- Length
- 665 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x661f92Fc5950020C7aB410B5F5b9a3f429F49Ae5
- Molecule
- RNA polymerase II-associated protein 3
- UniProt
- Q9H6T3
- Pockets
- 3 · best druggability 0.59
Structure
1 distinct chain · 56% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA polymerase II-associated protein 3 | protein | 665 | 56% helix, 0% strand | Q9H6T3 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 448 | 0.59 | 0.74 | 37 | empty |
| 2 | 87 | 0.32 | 0.73 | 12 | empty |
| 3 | 58 | 0.30 | 0.75 | 13 | empty |
Compared structures
- 6GXZ · Crystal structure of the human RPAP3(TPR2)-PIH1D1(CS) complex · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 6GXZ · Crystal structure of the human RPAP3(TPR2)-PIH1D1(CS) complex · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 6EZ4 · NMR structure of the C-terminal domain of the human RPAP3 protein · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 4CGV · First TPR of Spaghetti (RPAP3) bound to HSP90 peptide SRMEEVD · an experimental structure of the same protein · chain A against B, TM-score 0.19
- 4CGV · First tpr of spaghetti (RPAP3) bound to HSP90 peptide srmeevd · an experimental structure of the same protein · chain A against B, TM-score 0.19
- 6FD7 · NMR structure of the first TPR domain of the human RPAP3 protein · an experimental structure of the same protein · chain A against A, TM-score 0.19
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H6T3
- Elsewhere: UniProt Q9H6T3 · AlphaFold DB Q9H6T3
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