UniProt Q9H6T3
RNA polymerase II-associated protein 3 (Q9H6T3)
RNA polymerase II-associated protein 3 (UniProt Q9H6T3): 16 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H6T3
- Protein
- RNA polymerase II-associated protein 3
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
17 records of Q9H6T3 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4CGV | First TPR of Spaghetti (RPAP3) bound to HSP90 peptide SRMEEVD | x-ray diffraction | A, B, C, D | — | — |
| 4CGV | First tpr of spaghetti (RPAP3) bound to HSP90 peptide srmeevd | x-ray diffraction | A, B, C, D | — | — |
| 4CGW | Second TPR of Spaghetti (RPAP3) bound to HSP90 peptide SRMEEVD | x-ray diffraction | A, B | — | — |
| 4CGW | Second tpr of spaghetti (RPAP3) bound to HSP90 peptide srmeevd | x-ray diffraction | A, B | — | — |
| 6EZ4 | NMR structure of the C-terminal domain of the human RPAP3 protein | solution nmr | A | — | — |
| 6EZ4 | NMR structure of the C-terminal domain of the human RPAP3 protein | solution nmr | A | — | — |
| 6FD7 | NMR structure of the first TPR domain of the human RPAP3 protein | solution nmr | A | — | — |
| 6FD7 | NMR structure of the first tpr domain of the human RPAP3 protein | solution nmr | A | — | — |
| 6FDP | NMR structure of the second tpr domain of the human RPAP3 protein in complex with HSP90 peptide… | solution nmr | A | — | — |
| 6FDT | NMR structure of the second TPR domain of the human RPAP3 protein in complex with HSP70 peptide… | solution nmr | A | — | — |
| 6FDT | NMR structure of the second tpr domain of the human RPAP3 protein in complex with HSP70 peptide… | solution nmr | A | — | — |
| 6FM8 | RPAP3 C-terminus | x-ray diffraction | A | — | — |
| 6FO1 | Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 rbd domain from RPAP3. | electron microscopy | G | — | — |
| 6GXZ | Crystal structure of the human RPAP3(TPR2)-PIH1D1(CS) complex | x-ray diffraction | A, C | CA | — |
| 6GXZ | Crystal structure of the human RPAP3(TPR2)-PIH1D1(CS) complex | x-ray diffraction | A, C | CA | — |
| 6ZBK | Crystal structure of the human complex between RPAP3 and trbp | x-ray diffraction | A | — | — |
| Q9H6T3 | AlphaFold monomer V2.0 prediction for RNA polymerase II-associated protein 3 (Q9H6T3) | predicted | A | — | 3 (best 0.59) |
Ligands
- CA · Calcium ion · in 2 records
Experiment against prediction
- 6ZBK chain A against the predicted model Q9H6T3: TM-score 0.99, RMSD 0.38 Å
- 4CGV chain A against the predicted model Q9H6T3: TM-score 0.98, RMSD 0.54 Å
- 4CGV chain A against the predicted model Q9H6T3: TM-score 0.98, RMSD 0.54 Å
- 4CGV chain B against the predicted model Q9H6T3: TM-score 0.98, RMSD 0.79 Å
- 4CGV chain B against the predicted model Q9H6T3: TM-score 0.98, RMSD 0.79 Å
- 4CGV chain C against the predicted model Q9H6T3: TM-score 0.97, RMSD 0.87 Å
- 4CGV chain C against the predicted model Q9H6T3: TM-score 0.97, RMSD 0.87 Å
- 4CGV chain D against the predicted model Q9H6T3: TM-score 0.96, RMSD 0.83 Å
- 4CGV chain D against the predicted model Q9H6T3: TM-score 0.96, RMSD 0.83 Å
- 6FDP chain A against the predicted model Q9H6T3: TM-score 0.96, RMSD 0.93 Å
Elsewhere
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