MolNFT v1 · #384915 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I and III subunit RPAC1 (O15160)
O15160: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I and III subunit RPAC1 (O15160)”. 1 pocket (best druggability 0.51). MolNFT v1 #384915 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O15160
- Type
- protein
- Length
- 346 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7b8e62e0dcf0Bf4048333668837dF89841F58c0C
- Molecule
- DNA-directed RNA polymerases I and III subunit RPAC1
- UniProt
- O15160
- Pockets
- 1 · best druggability 0.51
Structure
1 distinct chain · 29% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerases I and III subunit RPAC1 | protein | 346 | 29% helix, 34% strand | O15160 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 233 | 0.51 | 0.76 | 22 | empty |
Compared structures
- 7FJI · human Pol III elongation complex · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 7FJI · Human pol III elongation complex · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 7FJJ · human Pol III pre-termination complex · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 7FJJ · Human pol III pre-termination complex · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 8ITY · human RNA polymerase III pre-initiation complex closed DNA 1 · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 8IUH · RNA polymerase III pre-initiation complex open complex 1 · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 7A6H · Cryo-EM structure of human apo RNA Polymerase III · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 7A6H · Cryo-EM structure of human apo RNA polymerase III · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 7AE1 · Cryo-EM structure of human RNA polymerase III elongation complex 1 · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 7AE1 · Cryo-EM structure of human RNA Polymerase III elongation complex 1 · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 7AE3 · Cryo-EM structure of human RNA polymerase III elongation complex 3 · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 7AE3 · Cryo-EM structure of human RNA Polymerase III elongation complex 3 · an experimental structure of the same protein · chain A against C, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O15160
- Elsewhere: UniProt O15160 · AlphaFold DB O15160
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