GL1X · GenesisL1 explorer

Research workbench

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I and III subunit RPAC1 (O15160)

Analyse AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I and III… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
O15160
Type
protein
Length
346 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x7b8e62e0dcf0Bf4048333668837dF89841F58c0C
Molecule
DNA-directed RNA polymerases I and III subunit RPAC1
UniProt
O15160
Pockets
1 · best druggability 0.51

Structure

1 distinct chain · 29% helix, 34% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA-directed RNA polymerases I and III subunit RPAC1protein34629% helix, 34% strandO15160

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12330.510.7622empty

Compared structures

  • 7FJI · human Pol III elongation complex · an experimental structure of the same protein · chain A against C, TM-score 0.98
  • 7FJI · Human pol III elongation complex · an experimental structure of the same protein · chain A against C, TM-score 0.98
  • 7FJJ · human Pol III pre-termination complex · an experimental structure of the same protein · chain A against C, TM-score 0.98
  • 7FJJ · Human pol III pre-termination complex · an experimental structure of the same protein · chain A against C, TM-score 0.98
  • 8ITY · human RNA polymerase III pre-initiation complex closed DNA 1 · an experimental structure of the same protein · chain A against C, TM-score 0.98
  • 8IUH · RNA polymerase III pre-initiation complex open complex 1 · an experimental structure of the same protein · chain A against C, TM-score 0.98
  • 7A6H · Cryo-EM structure of human apo RNA Polymerase III · an experimental structure of the same protein · chain A against C, TM-score 0.98
  • 7A6H · Cryo-EM structure of human apo RNA polymerase III · an experimental structure of the same protein · chain A against C, TM-score 0.98
  • 7AE1 · Cryo-EM structure of human RNA polymerase III elongation complex 1 · an experimental structure of the same protein · chain A against C, TM-score 0.98
  • 7AE1 · Cryo-EM structure of human RNA Polymerase III elongation complex 1 · an experimental structure of the same protein · chain A against C, TM-score 0.98
  • 7AE3 · Cryo-EM structure of human RNA polymerase III elongation complex 3 · an experimental structure of the same protein · chain A against C, TM-score 0.98
  • 7AE3 · Cryo-EM structure of human RNA Polymerase III elongation complex 3 · an experimental structure of the same protein · chain A against C, TM-score 0.98

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.