MolNFT v1 · #380721 · protein
AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RNF25 (Q96BH1)
Q96BH1: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase RNF25 (Q96BH1)”. 3 pockets (best druggability 0.46). MolNFT v1 #380721 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q96BH1
- Type
- protein
- Length
- 459 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBeB220F0B5b0C48F46B5DDd3E3b071BC0827f8D6
- Molecule
- E3 ubiquitin-protein ligase RNF25
- UniProt
- Q96BH1
- Pockets
- 3 · best druggability 0.46
Structure
1 distinct chain · 24% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase RNF25 | protein | 459 | 24% helix, 8% strand | Q96BH1 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 111 | 0.46 | 0.79 | 24 | empty |
| 2 | 108 | 0.41 | 0.76 | 21 | empty |
| 3 | 57 | 0.30 | 0.75 | 14 | empty |
Compared structures
- 2DMF · An extended conformation of the rwd domain of human ring finger protein 25 · an experimental structure of the same protein · chain A against A, TM-score 0.26
- 2DMF · An extended conformation of the RWD domain of human Ring finger protein 25 · an experimental structure of the same protein · chain A against A, TM-score 0.26
- 2DAY · Solution structure of the RWD domain of human ring finger protein 25 · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 2DAY · Solution structure of the rwd domain of human ring finger protein 25 · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 5D1L · Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 (Y165A) · an experimental structure of the same protein · chain A against B, TM-score 0.23
- 5D1L · Crystal structure of UBCH5B in complex with the ring-U5BR fragment of AO7 (Y165A) · an experimental structure of the same protein · chain A against B, TM-score 0.23
- 5D1M · Crystal structure of UBCH5B in complex with the ring-U5BR fragment of AO7 (P199A) · an experimental structure of the same protein · chain A against B, TM-score 0.23
- 5D1M · Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 (P199A) · an experimental structure of the same protein · chain A against B, TM-score 0.23
- 5D1K · Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 · an experimental structure of the same protein · chain A against B, TM-score 0.23
- 5D1K · Crystal structure of UBCH5B in complex with the ring-U5BR fragment of AO7 · an experimental structure of the same protein · chain A against B, TM-score 0.23
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96BH1
- Elsewhere: UniProt Q96BH1 · AlphaFold DB Q96BH1
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